Euphoria star Eric Dane diagnosed with ALS: Here’s why he is already back on set
Euphoria actor Eric Dane has revealed his diagnosis of ALS, a progressive neurological condition. Despite the life-altering news, the actor remains hopeful and plans to return to filming Euphoria’s third season. Known for playing Cal Jacobs and Grey’s Anatomy’s Mark Sloan, Dane is prioritising family and strength as he battles this new challenge.

Okay, deep breaths, Eric Dane, aka the complicated and chaotic daddy Cal Jacobs from Euphoria, has just dropped a life-altering update that has left fans stunned. The 52-year-old actor has been diagnosed with ALS (amyotrophic lateral sclerosis)—a degenerative neurological disorder that gradually weakens muscles and messes with voluntary movement. Yes, it is the same condition that affected the legendary Stephen Hawking.
Euphoria star Eric Dane diagnosed with ALS | Credit: X
Eric Dane announced the life-altering update of his life
In a heartfelt update shared with PEOPLE magazine, Dane, who was mainly seen in the show Grey's Anatomy, oh well, as a doctor, opened up about his diagnosis and how his family is rallying behind him during this difficult time. He shared that while the news has been tough, he is incredibly grateful for his loved ones and the unwavering support they are giving him. According to the Grey’s Anatomy alum, his plan is to keep pushing forward with hope—and he is not giving up on his career either.
Euphoria star Eric Dane diagnosed with ALS | Credit: X
Here’s why Eric Dane is back on set already
In fact, Dane has confirmed that he is heading back to the Euphoria set next week as production for season 3 begins. Fans can rest easy—Cal Jacobs is not done stirring the pot just yet. Dane feels lucky that he can still work and is reportedly looking forward to returning to what he loves, even as he asks for privacy to focus on his health and his family.
For those who know him best as McSteamy (yes, we will never forget Grey’s Anatomy), this update hits hard. Dane, who shares two daughters—Billie Beatrice and Georgia Geraldine—with actress Rebecca Gayheart, is now facing an uphill battle. But if there is one thing we know about him, it is that he does not back down easily.
Euphoria star Eric Dane diagnosed with ALS | Credit: X
ALS may not have a cure yet, but with increased awareness and ongoing research, more treatments are emerging to help slow its progression. Dane joins a list of public figures—including Aaron Lazar, Roberta Flack, and the late Kenneth Mitchell—who have bravely opened up about their diagnoses in recent years.
So yes, it is emotional, it is raw, and it is a lot to take in. But if anyone can power through with poise, purpose, and a bit of sass, it is Eric Dane.